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Autonomic nervous system

The autonomic nervous system (ANS or visceral nervous system) is the part of the peripheral nervous system that acts as a control system functioning largely below the level of consciousness, and controls visceral functions. The ANS affects heart rate, digestion, respiration rate, salivation, perspiration, diameter of the pupils, micturition (urination), and sexual arousal. Whereas most of its actions are involuntary, some, such as breathing, work in tandem with the conscious mind.

It is classically divided into two subsystems: the parasympathetic nervous system and sympathetic nervous system. Relatively recently, a third subsystem of neurons that have been named 'non-adrenergic and non-cholinergic' neurons (because they use nitric oxide as a neurotransmitter) have been described and found to be integral in autonomic function, particularly in the gut and the lungs.

With regard to function, the ANS is usually divided into sensory (afferent) and motor (efferent) subsystems. Within these systems, however, there are inhibitory and excitatorysynapses between neurons.

The enteric nervous system is sometimes considered part of the autonomic nervous system, and sometimes considered an independent system.


ANS innervation is divided into sympathetic nervous system and parasympathetic nervous system divisions. The sympathetic division has thoracolumbar “outflow�, meaning that the neurons begin at the thoracic and lumbar (T1-L2) portions of the spinal cord. The parasympathetic division has craniosacral “outflow�, meaning that the neurons begin at the cranial nerves (CN 3, CN7, CN 9, CN10) and sacral (S2-S4) spinal cord.

The ANS is unique in that it requires a sequential two-neuron efferent pathway; the preganglionic neuron must first synapse onto a postganglionic neuron before innervating the target organ. The preganglionic, or first, neuron will begin at the “outflow� and will synapse at the postganglionic, or second, neuron’s cell body. The post ganglionic neuron will then synapse at the target organ.

Sympathetic division

The sympathetic division (thoracolumbar outflow) consists of cell bodies in the lateral horn of spinal cord (intermediolateral cell columns) of the spinal cord from T1 to L2. These cell bodies are GVE neurons (general visceral efferent), and are the preganglionic neurons. There are several locations upon which preganglionic neurons can synapse for their postganglionic neurons:

These ganglia provide the postganglionic neurons from which innervation of target organs follows. Examples of splanchnic (visceral) nerves are:

  • Cervical cardiac nerves & thoracic visceral nerves which synapse in the sympathetic chain
  • Thoracic splanchnic nerves (greater, lesser, least) which synapse in the prevertebral ganglion
  • Lumbar splanchnic nerves which synapse in the prevertebral ganglion
  • Sacral splanchnic nerves which synapse in the inferior hypogastric plexus

These all contain afferent (sensory) nerves as well, also known as GVA neurons (general visceral afferent).

Parasympathetic division

The parasympathetic division (craniosacral outflow) consists of cell bodies from one of two locations: brainstem (Cranial Nerves 3, 7, 9, 10) or sacral spinal cord (S2, S3, S4). These are the preganglionic neurons, which synapse with postganglionic neurons in these locations:

  • Parasympathetic ganglia of the head (Ciliary (CN3), Submandibular (CN7), Pterygopalatine (CN7), Otic (CN9))
  • In or near wall of organ innervated by Vagus (CN10), Sacral nerves (S2, S3, S4))

These ganglia provide the postganglionic neurons from which innervations of target organs follows. Examples are:

  • The preganglionic parasympathetic splanchnic (visceral) nerves
  • Vagus nerve, which wanders through the thorax and abdominal regions innervating, among other organs, the heart, lungs, liver and stomach

Sensory neurons

The sensory arm is made of “primary visceral sensory neurons� found in the peripheral nervous system (PNS), in “cranial sensory ganglia�: the geniculate, petrosal and nodose ganglia, appended respectively to cranial nerves VII, IX and X. These sensory neurons monitor the levels of carbon dioxide, oxygen and sugar in the blood, arterial pressure and the chemical composition of the stomach and gut content. (They also convey the sense of taste, a conscious perception). Blood oxygen and carbon dioxide are in fact directly sensed by the carotid body, a small collection of chemosensors at the bifurcation of the carotid artery, innervated by the petrosal (IXth) ganglion. Primary sensory neurons project (synapse) onto “second order� or relay visceral sensory neurons located in the medulla oblongata, forming the nucleus of the solitary tract (nTS), that integrates all visceral information. The nTS also receives input from a nearby chemosensory center, the area postrema, that detects toxins in the blood and the cerebrospinal fluid and is essential for chemically induced vomiting or conditional taste aversion (the memory that ensures that an animal which has been poisoned by a food never touches it again). All these visceral sensory informations constantly and unconsciously modulate the activity of the motor neurons of the ANS

Motor neurons

Motor neurons of the ANS are also located in ganglia of the PNS, called “autonomic ganglia�. They belong to

From Yahoo Answers

Question:Hi, I know this question may seem weird, but it is a homework problem. Why is it that sometimes when a person gets really scared he/she wants to go to the bathroom badly? Why does this occur instead of the opposite, as normally expected? I know this sounds weird, but I need to know the answer in terms of the autonomic nervous system. Thanks!

Answers:That is work of adrenaline hormone the senses triggers this hormone to to perform these stress task this hormone triggers ADH hormone also in these condition hence you feel dry throat, more urine good cardiovascular activity etc.

Question:A.) has two efferent neurons B.) has two afferent neurons C.) stimulates its effector cells D.) has both afferent and efferent fibers


Question:10 POINTS FOR THE BEST ANSWER! :) and also, tell me stuff about the parasympathetic nervous system and the sympathetic nervous system :D

Answers:Full details in link. You can extract the info you need.

Question:You are walking through the forest and suddenly see a giant bear which freaks you out making your heart pound and you run away Describe the role of the autonomic nervous system and the endocrine system in this response. Make sure to detail the pathways involved in terms of location of different components (e.g. nuclei, ganglions, glands) their connectivity and the chemicals their secret.

Answers:please google for answer

From Youtube

Autonomic Nervous System :Review of the autonomic nervous system, comparing the divisions, the neurotransmitters and the receptors.

The Autonomic Nervous System :The Autonomic Nervous System - Sympathetic and parasympathetic nervous systems, control of heart rate, taxes and kineses. A2 Biology Revision (AQA Spec. A)